The initial findings revealed by this groundbreaking model reveal promising results for patients suffering from the horrid symptoms of mesothelioma.
An innovative new statistical model can aid in predicting the patients who have a greater likelihood of achieving a lifespan extension from undergoing surgical procedures to cure malignant pleural mesothelioma. These findings have been revealed in an article published by The Annals of Thoracic Surgery.
- A groundbreaking new statistical model can aid in identifying patients suffering from malignant pleural mesothelioma who are most likely to gain the life-extending advantages from surgical procedures.
- Patients who are young and have no history of exposure to asbestos along with an epithelioid histology and a lesser amount of ailing lymph nodes were directly linked with greater survival rates following surgical procedures.
- There is need for extensive research and further inquiry to fully validate the mechanisms used by the statistical model and examine its usefulness while dealing with patients in real-life settings.
Understanding Malignant Pleural Mesothelioma
Malignant pleural mesothelioma is a stubborn and fast-spreading form of cancer that impacts the pleura, which is basically the lining surrounding the chest cavity. Researchers have identified prolonged and repetitive exposure to asbestos as the greatest cause that triggers the development of mesothelioma.
Basically, asbestos is a group of minerals that occur naturally within the soil and rocks in various parts across the globe. Previously, asbestos was a prime product in making fireproof products, such as insulation equipment, fireproof gloves, flooring and theatre curtains amongst many others.
Statistics reveal that every year, nearly 3000 cases of mesothelioma have been diagnosed in the US alone, while the statistics are much higher for the entire world. Researchers have noticed a lag duration of twenty years or even more between the exposure to asbestos and the onset of the cancer. At the moment, scientists have not devised a cure for treating advanced stage mesothelioma, and research reveals that only 10% of the patients tend to have a 5-year survival rate.
How can this Statistical Model Change Treatments for MPM?
The therapy procedures for treating malignant pleural mesothelioma are criticized as being slightly controversial, and experts have not reached a unanimous decision on the appropriate surgical method to cut out this cancer. This groundbreaking new study on statistic model has revealed various clinical and surgical factors that can identify the patients who are likely to reap greater benefits from surgical procedures, and this can help both doctors and patients in figuring the best course of treatment to root out the illness.
The researchers examined the cases of 468 patients suffering from malignant pleural mesothelioma who had been operated for an extrapleural pneumonectomny (EPP). EPP is basically a surgical procedure in which doctors take out a lung, the diaphragm, the lining of the heart and the ailing chest lining. Results from studies conducted in the past revealed an average survival rate of 10 months for patients who had undergone the EPP as a standalone treatment.
However, according to the results revealed by this new study, 107 MPM patients who had undergone the extrapleural pneumonectomny, nearly 22.9% of the sample group, and survived for more than 3 years following their surgery. The traits that were directly linked with greater long-term survival were younger patients, no history of exposure to asbestos, a lesser amount of lymph nodes and suffering from an epithelioid kind of mesothelioma.
These findings indicate that the researchers have managed to build an innovative system of scores that takes into account the patient traits mentioned above. The model is very comprehensive and easy to operate, and it aid experts and doctors in improving the outcomes of the treatments, and naturally, tailoring the surgical and post-surgical treatments according to the surveillance needs of the patients. Moreover, it can also identify the patients who require a much more aggressive course of cancer treatment. Sadly, despite undergoing surgery, this treacherous disease still has a bad prognosis.
Needless to say, there is still need for further inquiry in order to generalize and fully validate the findings of the statistical scoring model in order to examine its usefulness in real-life clinical settings.